CÔNG BỐ KHOA HỌC​

Key findings: Detect ctDNA in 90.5% of the pre-operative plasma samples, whereas carcinoembryonic antigen (CEA) was elevated in only 41.3% of them.

Key findings: Asian cohorts show higher TP53 mutation frequency than in Caucasians. Alterations in PIK3CA and PI3K signaling were dominant.

Key findings: Develop a personalized, tumor-informed assay to detect circulating tumor DNA (ctDNA) in liquid biopsy with high sensitivity and specificity using ultra-deep next-generation sequencing (NGS)

Key findings: Evaluate SPOT-MAS performance on detection of 4 common cancer types: AUC 0.93; SEN: 73.9%; SPEC 95.9%

Key findings: Evaluate plasma mutations as blomarkers for early detection of CRC: SENS: 56%, SPEC: 98.95%

Key findings: Explore methylation signatures of 122 NSCLC patients with TKI drug resistance