ABOUT ME
- E-mail: [email protected]
- University of Natural Sciences, Vietnam - B.S. in Biotechnology, 1999 - 2003
- University of Paris XI, Orsay and University of Natural Sciences, HCM city - MS. in Genetics, 2004 - 2006
- Oklahoma State University, Stillwater, OK - Ph.D. in Molecular genetics, 2007 - 2011
- Johns Hopkins University School of Medicine, Baltimore, MD - Postdoc Fellow. in Cancer biology, 2011 - 2014
- U.S. National Institutes of Health - NIEHS, Research Triangle Park, NC - Research Fellow. in Signal transduction - Cancer metabolism, 2015 - 2016
HONORS
- 2016: U.S. National Institutes of Health (NIH) Fellow Award for Excellent Research, NIH
- 2010-2011:Edward Grula distinguished graduate fellowship, Oklahoma State University
- 2005: Europe Union scholarship (DUO-France program), University of Paris XI
- 2004: Agence Universitaire de la Francophonie scholarship, INSA-Toulouse
- 2003: Excellent graduation award, Vietnam National University
EXPERIENCES
TIMELINE
2007
2011
2015
2017
PUBLICATIONS
SELECTED
- Hoai-Nghia Nguyen and Jeffrey A Hadwiger. The Gα4 G protein subunit interacts with the MAP kinase ERK2 using a D-motif that regulates developmental morphogenesis in Dictyostelium. Developmental Biology. 2009 Nov 15; 335(2): 385-95.
- Hoai-Nghia Nguyen, Brent Raisley and Jeffrey A Hadwiger. MAP kinases have different functions in Dictyostelium G protein-mediated signaling. Cell Signal. 2010 May, 22 (5): 836-84
- Nguyen HN, Afkari Y, Senoo H, Sesaki H, Devreotes PN, Iijima M. Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium. Oncogene. 2013 Dec.
- Hoai-Nghia Nguyen, Jr-Ming Yang, Yashar Afkari, Ben Ho Park, Hiromi Sesaki, Peter N. Devreotes, and Miho Iijima. ePTEN: an Enhanced PTEN with Increased Tumor Suppressor Activities. Proc. Natl. Acad. Sci. U.S.A. June 16, 2014.
- Hoai-Nghia Nguyen, Jr-Ming Yang, Ben Ho Park, Hiromi Sesaki, Peter N. Devreotes, and Miho Iijima. A New Class of Cancer-Associated PTEN Mutations Defined by Membrane Translocation Defects. Oncogene. 2015 Jul;34(28):3737-43.
- Jr-Ming Yang*, Paula Schiapparelli*, Hoai-Nghia Nguyen*, Qiang Zhang, Sara Abbadi, Mario Amzel, Hiromi Sesaki, Alfredo Quinones-Hinojosa, Miho Iijima. Characterization of PTEN mutations in brain cancer reveals that PTEN mono-ubiquitination promotes protein stability and nuclear localization. Oncogene 2017 Mar 6. (* these authors have equal contribution)
- Chunfang Gu, Hoai-Nghia Nguyen, Douglas Ganini, Zhaowei Chen, Henning J Jessen, Zhen Gu, Huanchen Wang, Stephen B Shears. KO of 5-InsP7 kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotype. Proc. Natl. Acad. Sci. U.S.A. 2017
- Hoai-Nghia Nguyen, Ngoc-Phuong Thi Cao, Thien-Chi Van Nguyen, Khang Nguyen Duy Le, Dat Thanh Nguyen, Quynh-Tho Thi Nguyen, Thai-Hoa Thi Nguyen, Chu Van Nguyen, Ha Thu Le, Mai-Lan Thi Nguyen, Trieu Vu Nguyen, Vu Uyen Tran, Bac An Luong, Linh Gia Hoang Le, Quoc Chuong Ho, Hong-Anh Thi Pham, Binh Thanh Vo, Luan Thanh Nguyen, Anh-Thu Huynh Dang, Sinh Duy Nguyen, Duc Minh Do, Thanh-Thuy Thi Do, Anh Vu Hoang, Kiet Truong Dinh, Minh-Duy Phan, Hoa Giang, Le Son Tran. Liquid biopsy uncovers distinct patterns of DNA methylation and copy number changes in NSCLC patients with different EGFR-TKI resistant mutations. Scientific Reports. 2021
